#D-105 AAD 2024 - September 2025

Early Intervention in Vitiligo: Outcomes and Predictors

Dr. Daniel Garcia, Dr. Michelle White, Dr. Brian Miller, Dr. Angela Rodriguez
Therapeutic Area: Dermatology
Study Type: Observational Study

Key Findings

Early treatment within 6 months of onset achieved 75% repigmentation vs 28% for delayed treatment. Facial lesions responded best.

Summary

Early treatment within 6 months of onset achieved 75% repigmentation vs 28% for delayed treatment. Facial lesions responded best.

Study Design

Prospective cohort study of 280 patients with recent-onset vitiligo followed for 12 months.

Methods

Patients stratified by time from onset to treatment. Interventions included topicals, phototherapy, or combination.

Results

Early treatment: 75% ≥50% repigmentation vs 28% delayed. Face/neck: 82% vs 44%. Trunk: 51% vs 18%.

Conclusions

Early intervention critical for vitiligo repigmentation. Facial areas most responsive regardless of treatment timing.

Full Abstract

This study examined early intervention in vitiligo: outcomes and predictors in a comprehensive clinical investigation.